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2009 FABIAN, C., MEYER, S., SATTLER, U., HOERNER, C., MUELLER-KLIESER, W.: Laktatmessung in vitro und ex vivo: Eine vergleichende Studie in humanen Plattenepithelkarzinomlinien Exp Strahlenther Klin Strahlenbiol. 18, 22-24 (2009) GROTIUS, J., DITTFELD, C., HUETHER, M., MUELLER-KLIESER, W., BAUMANN, M., KUNZ-SCHUGHART, L.K.: Impact of exogenous lactate on survival and radioresponse of carcinoma cells in vitro Int J Radiat Biol. 2009: in press GROTIUS, J., SEIDEL, C., HUETHER, M., MUELLER-KLIESER, W., BAUMANN, M., KUNZ-SCHUGHART, L.K.: Impact of exogenous lactate on survival and radioresponse of carcinoma cells Exp Strahlenther Klin Strahlenbiol. 18, 13-14 (2009) HIRSCHAEUSER, F., LEIDIG, T., RODDAY, B., LINDEMANN, C., MUELLER-KLIESER, W.: Test system for trifunctional antibodies in 3D MCTS culture J Biomol Screen. 14(8), 980-990 (2009) MEYER, S., WENZEL, E., YAROMINA, A., WALENTA, S., ZIPS, D., BAUMANN, M., MUELLER-KLIESER, W.: Expression glykolyse-assoziierter Gene in UT-SCC-14 Tumoren während fraktionierter Bestrahlung Exp Strahlenther Klin Strahlenbiol. 18, 35-38 (2009) MEYER, S., YAROMINA, A., WALENTA, S., ZIPS, D., BAUMANN, M., MUELLER-KLIESER, W.: Metabolic and genomic changes in tumor xenografts during fractionated radiotherapy Molecular Radiation Biology, Oncology (Proceedings of the 11th International Wolfsberg Meeting). 8, 94 (2009) SATTLER, U., HIRSCHHAEUSER, F., MUELLER-KLIESER, W.: Manipulation of Glycolysis in Malignant Tumors: Fantasy or Therapy? Current Medicinal Chemistry. 2009: in press SATTLER, U., MUELLER-KLIESER, W.: The Anti-oxidant Capacity of Tumor Glycolysis Int J Radiat Biol. 2009: in press YAROMINA, A., QUENNET, V., ZIPS, D., MEYER, S., SHAKIRIN, G., WALENTA, S., MUELLER-KLIESER, W., BAUMANN, M.: Co-localization of hypoxia and perfusion markers with parameters of glucose metabolism in human squamous cell carcinoma (hSCC) xenografts Int J Radiat Biol. 2009: in press ZIEBART, T., WALENTA, S., SATTLER, U., KUNKEL, M., WAGNER, W., MUELLER-KLIESER, W.,: Detektion von Metaboliten mit induzierter Biolumineszenz in Tumoren des Kopf-Hals-Bereiches zur Tumorprädiktion HNO. 2009: in press 2008 GOETZE, K., SCHOLZ, M., TAUCHER-SCHOLZ, G. und MUELLER-KLIESER, W.: Änderungen der Migration und Expression der Proteinkase Akt1 in Tumorzellen nach Röntgen- und Schwerionenbestrahlung in vitro. Exp. Strahlenther. Klin. Strahlenbiol. 17, 79-82 (2008) FAVARO, E., NARDO, G., PERSANO, L., MASIERO, M., MOSERLE, L., ZAMARCHI, R., ROSSI, E., ESPOSITO, G., PLEBANI, M., SATTLER, U., MANN, T., MUELLER-KLIESER, W., CIMINALE, V., AMADORI, A., INDRACCOLO, S.,: Hypoxia inducible Factor-1a inactivation unveils a link between tumor cell metabilism and hypoxia-induced cell death. Am.J.Pathol. 173(4), 1186-201 (2008) SCHAEFER, C., MEYER, S.S., LEIDIG, T., GOETZE, K., WALENTA, S. und MUELLER-KLIESER, W.: Glykolytische Aktivität und Strahlenresistenz verschiedener Plattenepithel-KarzinomzellLinien in vitro. Exp. Strahlenther. Klin. Strahlenbiol. 17, 149-153 (2008) 2007 GOETZE, K., SCHOLZ, M., TAUCHER-SCHOLZ, G. und MUELLER-KLIESER, W.: Änderungen der Migration und Expression der Proteinkase Akt1 in Tumorzellen nach Röntgen- und Schwerionenbestrahlung in vitro. Exp. Strahlenther. Klin. Strahlenbiol. 16, 7-10 (2007) GOETZE, K., SCHOLZ, M., TAUCHER-SCHOLZ, G. and MUELLER-KLIESER, W.: The impact of conventional and heavy ion irradiation on tumor cell migration in vitro. Int. J. Radiat. Biol. 83(11-12), 889-896 (2007) SCHMID, S. A., GAUMANN, A., WONDRAK, M., ECKERMANN, C., SCHULTE, S., MUELLER-KLIESER, W., WHEATLEY, D. N. and KUNZ-SCHUGHART: Lactate adversely affects the in vitro formation of endothelial cell tubular structures through the action of TGF-b1. Exp. Cell Res. 313, 2531-2549 (2007) TOPSCH, J., SCHOLZ, M. and MUELLER-KLIESER, W.: Radiobiological characterization of human tumor cell multilayers after conventional and particle irradiation. Radiat. Res. 167, 645-654 (2007) SATTLER, U., WALENTA, S. and MUELLER-KLIESER, W.: Laktat und Redoxstatus in malignen Tumoren - Medizin aktuell. Der Anaesthesist 56(5), 466-469 (2007) SATTLER, U., WALENTA, S. and MUELLER-KLIESER, W.: Bestimmung des regionalen Laktat/Pyruvat-Verhältnisses in Geweben. Exp. Strahlenther. Klin. Strahlenbiol. 16, 7-10 (2007) SATTLER, U., WALENTA, S. and MUELLER-KLIESER, W.: A bioluminescence technique for quantitative and structure-associated imaging of pyruvate. Lab. Invest. 87, 84-92 (2007) 2006 QUENNET, V., A. YAROMINA, D. ZIPS, A. ROSNER, S. WALENTA, M. BAUMANN, W. MUELLER-KLIESER: Tumor lactate content predicts for response to fractionated irradiation of human squamous cell carcinomas in nude mice. Radiother. Oncol. 81: 130-135 (2006) YAROMINA, A., D. ZIPS, H.D. THAMES, W. EICHELER, M. KRAUSE, A. ROSNER, M. HAASE, C. PETERSEN, J.A. RALEIGH, V. QUENNET, S. WALENTA, W. MUELLER-KLIESER, M. BAUMANN: Pimonidazole labelling and response to fractionated irradiation of five human squamous cell carcinoma (hSCC) cell lines in nude mice: the need for a multivariate approach in biomarker studies. Radiother. Oncol. 81: 122-129 (2006) QUENNET, V., U. SATTLER, A. YAROMINA, D. ZIPS, A. ROSNER, S. WALENTA, M. BAUMANN, W. MUELLER-KLIESER: Laktat- und Pyruvatkonzentrationen in Xenotransplantaten von humanen Kopf-Hals-Tumorlinien unterschiedlicher Radiosensivität. Exp. Strahlenther. Klin. Strahlenbiol. 15: 145-150 (2006) GOTTFRIED, E., L. A. KUNZ-SCHUGHART, S. EBNER, W. MUELLER-KLIESER, S. HOVES, R. ANDREESEN, A. MACKENSEN, M. KREUTZ: Tumor-derived lactic acid modulates dendritic cell activation and antigen expression. Blood 107(5): 213-221 (2006) 2005 BANNING, V., S. WALENTA, W. MUELLER-KLIESER: Charakterisierung des Glukosestoffwechsels in humanen xenotransplantierten Plattenepithelkarzinomen. Exp. Strahlenther. Klin. Strahlenbiol. 14: 7-1 (2005) SATTLER, U., S. WALENTA, W. MUELLER-KLIESER: Eine neue Biolumineszenzmethode zur quantitativen und lokalen Konzentrationsbestimmung von Pyruvat in kryofixiertem Gewebe. Exp. Strahlenther. Klin. Strahlenbiol. 14: 26-30 (2005) TOPSCH, J., W. MUELLER-KLIESER, M. SCHOLZ, G. KRAFT: Cell cycle effects contribute to multicellular radiosensitization. In: GSI Scientific Report 2004, Darmstadt, 2005, p. 290 (ISSN 0174-0814) 2004 STAAB, A., D. ZUKOWSKI, S. WALENTA, M. SCHOLZ, W. MUELLER-KLIESER: Response of V79 multicellular spheroids exposed to high energy carbon ions. Radiat. Res. 161: 219-227 (2004) BANNING, V., S. WALENTA, W. MUELLER-KLIESER: Bedeutung des Glukosestoffwechsels für die Strahlenempfindlichkeit maligner Tumoren. Exp. Strahlenther. Klin. Strahlenbiol. 13: 65-69 (2004) WALENTA, S., T. SCHROEDER, W. MUELLER-KLIESER: Lactate in solid malignant tumors: Potential basis of a metabolic classification in clinical oncology. Curr. Med. Chem. 11(16): 2195-2204 (2004) WALENTA, S., W. MUELLER-KLIESER: Lactate: Mirror and Motor of Tumor Malignancy. Sem. Radiat. Oncol. 14(3): 267-274 (2004) ZIPS, D., M. ADAM, M. FLENTJE, A. HAASE, M. MOLLS, W. MUELLER-KLIESER, C. PETERSEN, C. PHILBROOK, P. SCHMITT, O. THEWS, S. WALENTA, M. BAUMANN: Impact of Hypoxia and the Metabolic Microenvironment for Radiotherapy of Solid Tumors - Introduction of a Multiinstitutional Research Project. Strahlenther. Onkol. 10: 609-615 (2004) MUELLER-KLIESER, W.: Erythropoetin in Tumorpathophysiologie und Strahlentherapie: Zwei Kapitel voller Widersprüche? Exp. Strahlenther. Klin. Strahlenbiol. 13: 87, 2004 (ISSN 1432-864X) TOPSCH, J., W. MUELLER-KLIESER, M. SCHOLZ, G. KRAFT: Heavy ion irradiation and chemotherapy of multilayer culture. In: GSI Scientific Report 2003, Darmstadt, 2004, p. 167 (ISSN 0174-0814) 2003 WALENTA, S., T. V. CHAU, T. SCHROEDER, H.-A. LEHR, L. A. KUNZ-SCHUGHART, A. FUERST, W. MUELLER-KLIESER: High lactate levels in primary human rectal adenocarcinomas are correlated with synchronous distant metastasis. J. Cancer Res. Clin. Oncol. 129(6): 321-326 (2003) TOPSCH, J., W. MUELLER-KLIESER, M. SCHOLZ, G. KRAFT: Heavy ion irradiation of multilayer culture. In: GSI Scientific Report 2002, Darmstadt, 2003, p. 162 (ISSN 0174-0814) 2002 WALENTA, S., T. SCHROEDER, W. MUELLER-KLIESER: Metabolic mapping with bioluminescence: basic and clinical relevance (Invited Review). Biomol. Engin. 18(6), 249-262 (2002) BORISJUK, L., S. WALENTA, H. ROLLETSCHEK, W. MUELLER-KLIESER, U. WOBUS, H. WEBER: Spatial analysis of plant metabolism: Sucrose imaging within Vicia faba cotyledons reveals specific developmental patterns. Plant J. 29(4), 521-530 (2002) WALENTA, S., B. FEIGK, I. WACHSMUTH, T. DUNKERN, H. DEGANI, W. MUELLER-KLIESER: Differential changes in purine nucleotides after doxorubicin treatment of human cancer cells in vitro. Int. J. Oncol. 21, 289-296 (2002) MUELLER-KLIESER, W., S. SCHREIBER-KLAIS, S. WALENTA, M. H. KREUTER: Bioactivity of well-defined green tea extracts in multicellular tumor spheroids. Int. J. Oncol. 21, 1307-1315 (2002) WALENTA, S., T. SCHROEDER, W. MUELLER-KLIESER: Regarding Tarnawski et al., IJROBP 2002;52:1271-1276 (Letter to the editor). Int. J. Radiat. Oncol. Biol. Phys. 54(5):1576 (2002) TOPSCH, J., W. MUELLER-KLIESER, M. SCHOLZ, G. KRAFT: Heavy ion irradiation of human colon adenocarcinoma cells in multilayer culture. In: GSI Scientific Report 2001, Darmstadt, 2002, p. 162 (ISSN 0174-0814) 2001 VON BÜLOW, C., W. HAYEN, A. HARTMANN, W. MUELLER-KLIESER, B. ALLOLIO, V. NEHLS: Endothelial capillaries chemotactically attract tumour cells. J. Pathol. 193(3), 367-376 (2001) WALENTA, S., S. SNYDER, Z. A. HAROON, R. D. BRAUN, K. AMIN, D. BRIZEL, W. MUELLER-KLIESER, B. CHANCE, M.W. DEWHIRST: Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model. Int. J. Radiat. Oncol. Biol. Phys. 51(3), 840-848 (2001) BRIZEL, D. M., T. SCHROEDER, R. L. SCHER, S. WALENTA, M. W. DEWHIRST, W. MUELLER-KLIESER: Elevated tumor lactate concentrations predict for an increased risk of metastases in head and neck cancer. Int. J. Radiat. Oncol. Biol. Phys. 51(2), 349-353 (2001) SCHREZENMEIR, J., A. HYDER, M. VREDEN, C. LAUE, W. MUELLER-KLIESER: Oxygen profiles of microencapsulated islets: effect of immobilised hemoglobin in the alginate matrix. Transpl. Proc. 33(7-8), 3511-3516 (2001) WINHART, S., W. MUELLER-KLIESER, M. SCHOLZ, G. KRAFT: Heavy ion irradiation of human colon adenocarcinoma multilayer cultures. In: GSI Scientific Report 2000, Darmstadt, 2001, p. 152 (ISSN 0174-0814) 2000 WALENTA, S., M. WETTERLING, M. LEHRKE, G. SCHWICKERT, K. SUNDFR, E. K. ROFSTAD, W. MUELLER-KLIESER: High lactate levels predict likelihood of metastases, tumor regrowth, and patient survival in human cervix cancers. Cancer Res. 60, 916-921 (2000) KUNZ-SCHUGHART, L. A., J. DOETSCH, W. MUELLER-KLIESER, K. GROEBE: Oncogene-associated proliferative and metabolic behavior of fibroblast spheroids in short and long term culture. Am. J. Physiol. 278(4), C765-C780 (2000) WALENTA, S., J. DOETSCH, W. MUELLER-KLIESER, L. A. KUNZ-SCHUGHART: Metabolic imaging in multicellular spheroids of oncogene-transfected fibroblasts. J. Histochem. Cytochem. 48, 509-522 (2000) MUELLER-KLIESER, W.: Multicellular tumor spheroids: tumor biology and experimental therapeutics (Invited review). Crit. Rev. Oncol. Hematol. 36, 123-139 (2000) KUNZ-SCHUGHART, L., W. MUELLER-KLIESER: Three-dimensional culture (Chapter 5). In: Animal Cell Culture: A Practical Approach. 3rd Edition, John R. W. Masters (ed.), IRL Press at Oxford University Press, Oxford, New York, Tokyo, 2000, pp. 123-148 WINHART, S., W. MUELLER-KLIESER, M. SCHOLZ: Radiobiological characterization of a human colon carcinoma cell line and introduction of a new three-dimensional cell culture system. In: GSI Scientific Report 1999, Darmstadt, 2000, pp. 157-158 (ISSN 0174-0814) 1999 WALGENBACH, S., A. BERMES, U. BERMES, F. BITTINGER, TH. JUNGINGER, W. MUELLER-KLIESER: Hyperlactacidaemia in isolated hyperthermic perfusion of tumour bearing rat limbs: a study of feasibility using a novel infusion solution. Int. J. Hyperthermia 15, 109-122 (1999) DUNKERN, T., W. MUELLER-KLIESER: Quantification of the apoptosis induction by doxorubicin in three types of human mammary carcinoma spheroids. Anticancer Res. 19(5), 3141-3146 (1999) ZUKOWSKI, D., A. STAAB, M. SCHOLZ, W. MUELLER-KLIESER: OER and RBE in spheroids with regard to different end points. In: GSI Scientific Report 1998, Darmstadt, 1999, pp. 135-136 (ISSN 0174-0814) 1998 BORISJUK, L., S. WALENTA, H. WEBER, W. MUELLER-KLIESER, U. WOBUS: High resolution histographical mapping of glucose concentrations in developing cotyledons of Vicia faba in relation to mitotic activity and storage processes: glucose as a possible developmental trigger. Plant J. 15, 583-591 (1998) ROMERO, F. J., W. MUELLER-KLIESER: Semiquantitative bioluminescent assay of glutathione. J. Biolumin. Chemilumin. 13, 1-4 (1998) MUELLER-KLIESER, W., P. VAUPEL, C. STREFFER: Energy status of malignant tumors in patients and experimental animals. In: Medical Radiology - Diagnostic Imaging and Radiation Oncology. Vol.: Blood Perfusion and Microenvironment of Human Tumors, M. Molls and P. Vaupel (eds.), Springer, Berlin, Heidelberg, 1998, pp. 121-132 FOURNIER, C., G. KRAFT, W. KRAFT-WEYRATHER, A. MITAROFF, S. RITTER, J. DEBUS, C. KARGER, H. PESCHKE, M. SCHOLZ, G. WOLBER, D. ZUKOWSKI, A. STAAB, W. MUELLER-KLIESER, Th. HERRMANN, H. ALHEIT, W. DÖRR, P. GEYER, R. KUMPF, W. ENGHARDT, R. HINZ: Radiobiology related to heavy ion therapy. In: GSI Scientific Report 1997, Darmstadt, 1998, pp. 149-151 1997 WALENTA, S., A. SALAMEH, H. LYNG, J. F. EVENSEN, M. MITZE, E. K. ROFSTAD, W. MUELLER-KLIESER: Correlation of high lactate levels in primary lesions of human head and neck with incidence of metastasis. Am. J. Pathol. 150, 409-415 (1997) ROMERO, F. J., ZUKOWSKI, D., W. MUELLER-KLIESER: Glutathione content of V79 cells in two- or three-dimensional culture. Am. J. Physiol. 272, C1507-C1512 (1997) MUELLER-KLIESER, W.: Three-dimensional cell cultures: From molecular mechanisms to clinical applications - Invited Review. Am. J. Physiol. 273, C1109-C1123 (1997) FOURNIER, C., G. KRAFT, W. KRAFT-WEYRATHER, S. RITTER, M. SCHOLZ, W. MUELLER-KLIESER, D. ZUKOWSKI, L. JÜHLING-POHLIT, B. SCHOPOHL, H. ALBEIT, W. DÖRR, W. ENGHARDT, P. GEYER, T. HERRMANN, R. KUMPF, H. NITZSCHE, H. RÖTHIG, M. SOBIELLA, R. WEISE, T. ZACHARIAS, J. DEBUS, H. PESCHKE, G. WOLBER: Radiobiology related to heavy ion therapy. In: GSI Scientific Report 1996, Darmstadt, 1997, pp. 142-144 (ISSN 0174-0814) ZUKOWSKI, D., M. SCHOLZ, G. KRAFT, W. MUELLER-KLIESER: Cellular response of V79 multicellular spheroids exposed to high energy carbon ions. 6th Workshop on Heavy-Charged Particles in Biology and Medicine, Bavena, Italy, 1997, In: GSI Scientific Report 1997-09, Darmstadt, 1997, D12 1996 GROEBE, K., W. MUELLER-KLIESER: On the relation between size of central necrosis and diameter of multicellular spheroids. Int. J. Radiat. Oncol. Biol. Phys. 34, 395-401 (1996) SCHWICKERT, G., S. WALENTA, W. MUELLER-KLIESER: Mapping and quantification of biomolecules in tumor biopsies using bioluminescence. Experientia 52, 460-463 (1996) MUELLER-KLIESER, W., S. WALENTA, D. K. KELLEHER, H. DINH, E. MARX, P. VAUPEL: Tumor growth inhibition by induced hyperlactemia, hyperglycemia, and localized hyperthermia. Int. J. Hyperther. 12, 501-511 (1996) KUNZ-SCHUGHART, L. A., K., GROEBE, W. MUELLER-KLIESER: Three-dimensional cell culture induces novel proliferative and metabolic alterations associated with oncogenic transformation. Int. J. Cancer 66, 1-9 (1996) FOURNIER, C., G. KRAFT, W. KRAFT-WEYRATHER, S. RITTER, M. SCHOLZ, W. MUELLER-KLIESER, I. WACHSMUTH, D. ZUKOWSKI, L. JÜHLING-POHLIT, B. SCHOPOHL, H. ALHEIT, W. DÖRR, W. ENGHARDT, C. GEIPEL, P. GEYER, P. HENZEL, T. HERRMANN, R. KUMPF, H. RÖTHIG, M. SOBIELLA, R. WEISE, T. ZACHARIAS, J. DEBUS, H. PESCHKE, G. WOLBER: Radiobiology related to heavy ion therapy. In: GSI Scientific Report 1995, Darmstadt, 1996, pp. 139-141 (ISSN 0174-0814) 1995 TEUTSCH, H. F., A. GOELLNER, W. MUELLER-KLIESER: Glucose levels and succinate and lactate dehydrogenase activity in EMT6/Ro tumor spheroids. Europ. J. Cell Biol. 66, 302-307 (1995) SCHWICKERT, G., S. WALENTA, K. SUNDFOR, E.K. ROFSTAD, W. MUELLER-KLIESER: Correlation of high lactate levels in human cervical cancer with incidence of metastasis. Cancer Res. 55, 4757-4759 (1995) KROEGER, M., S. WALENTA, E. K. ROFSTAD, W. MUELLER-KLIESER: Growth rates or radiobiological hypoxia are not correlated with local metabolite content in human melanoma xenografts with similar vascular network. Br. J. Cancer 72, 912-916 (1995) KUNZ-SCHUGHART, L. A., A. SIMM, W. MUELLER-KLIESER: Oncogene-associated transformation of rodent fibroblasts is accompanied by large morphologic and metabolic alterations. Oncol. Rep. 2, 651-661 (1995) GROSS, M. W., U. KARBACH, K. GROEBE, A. FRANKO, W. MUELLER-KLIESER: Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids. Int. J. Cancer 61, 1-7 (1995) GROEBE, K., S. ERZ, W. MUELLER-KLIESER: Glucose diffusion coefficients determined from concentration profiles in EMT6 tumor spheroids incubated in radioactively labeled L-glucose. In: Oxygen Transport to Tissue, Vol. XVI, Hogan et al. Hrsg., Plenum Press, New York, 1995, pp. 619-625 MUELLER-KLIESER, W., S. WALENTA, G. SCHWICKERT: Kartierung und Quantifizierung von Biomolekülen in Tumorbiopsien durch ein Biolumineszenzverfahren. Forschungsmagazin der Johannes Gutenberg-Universität Mainz, Sonderheft März/April 1995, pp. 44-52 SCHWICKERT, G., S. WALENTA, W. MUELLER-KLIESER: Biological and possible clinical relevance of metabolic imaging with bioluminescence. The 4th Medical Photonics Workshop and International Conference on Advanced Video-Microscopy, Hamamatsu University, Hamamatsu City, Japan, 1995, pp. 3-15 MUELLER-KLIESER, W.: Metabolic milieu - a response modifier in multicell spheroids. In: Proceedings of the Xth International Congress of Radiation Research, Wuerzburg, Germany, 1995, Vol. 2, pp. 827-830 MELZIG, M. F., A. M. WOBUS, W. MUELLER-KLIESER, D. BREITKREUTZ, S. WERNER, P. BOUKAMP, A. BADER, C. NIEHRS, N. E. FUSENIG: International Conference on Cell Interaction in Malignancy, Development and Differentiation (Editorial). Heidelberg, Germany, 1995, J. Cancer Res. Clin. Oncol. 121, 757-763 (1995) 1990-1994 DELLIAN, M., S. WALENTA, F. GAMARRA, G. E. H. KUHNLE, W. MUELLER-KLIESER, A. E. GOETZ: High energy shock waves enhance hyperthermic response of tumors: effects on blood flow, energy metabolism and tumor growth. J. Natl. Cancer Inst. 86, 287-293 (1994) SCHREZENMEIR, J., L. GERÖ, M. SOLHDJU, J. KIRCHGESSNER, Ch. LAUE, J. BEYER, H. STIER, W. MUELLER-KLIESER: Relation between secretory function and oxygen supply in isolated islet organs. Transpl. Proc. 26, 809-813 (1994) STIER, H., U. KARBACH, C.-D. GERHARZ, H. GABBERT, W. MUELLER-KLIESER: Oxygenation status of rhabdomyosarcoma spheroids with different stages of differentiation. Adv. Exp. Med. Biol. 345, 351-357 (1994) KUNZ, L.A., K. GROEBE, W. MUELLER-KLIESER: Oncogene-associated growth behavior and oxygenation of multicellular spheroids from rat embryo fibroblasts. Adv. Exp. Med. Biol. 345, 359-366 (1994) WALENTA, S., M. DELLIAN, A.E. GOETZ, W. MUELLER-KLIESER: Correlation between regional ATP and blood flow in tumors and surrounding normal tissue. Adv. Exp. Med. Biol. 345, 387-393 (1994) MUELLER-KLIESER, W., S. WALENTA, G. SCHWICKERT: Quantitative bioluminescence imaging - a method for the detection of metabolite distributions in frozen tissues. SPIE (International Society for Optical Engineering) Proceedings 2083, 34-40 (1994) MONZ, B., U. KARBACH, W. MUELLER-KLIESER: Oxygenation and cellular proliferation in spheroids from human colon adenocarcinoma cells. In: Regulation von Durchblutung und Sauerstoffversorgung der Organe, J. Grote und E. Witzleb (Hrsg.), Gustav Fischer Verlag, Stuttgart, pp. 181-188, 1994 MUELLER-KLIESER, W.: "Multicellular Spheroids", in: Cell & Tissue Culture: Laboratory Procedures, A. Doyle, J. B. Griffiths and D. G. Newell (eds.), Wiley & Sons, Chichester, England, 1994, pp. 5B8.1-5B8.5 SCHREZENMEIR J., J. KIRCHGESSNER, L. GEROE, L. A. KUNZ, J. BEYER, W. MUELLER-KLIESER,: Effect of microencapsulation on oxygen distribution in islet organs. Transplantation 57, 1308-1314 (1994) MONZ, B., U. KARBACH, K. GROEBE, W. MUELLER-KLIESER: Proliferation and oxygenation status of WIDR spheroids in different lactate and oxygen environments. Oncol. Rep. 1, 1177-1183 (1994) DELLIAN, M., S. WALENTA, G.E.H. KUHNLE, F. GAMARRA, W. MUELLER-KLIESER, A.E. GOETZ: Relation between autoradiographically measured blood flow and ATP concentrations obtained from imaging bioluminescence in tumors following hyperthermia. Int. J. Cancer 53, 785-791 (1993) DELLIAN, M., S. WALENTA, GAMARRA, F., G.E.H. KUHNLE, W. MUELLER-KLIESER, A.E. GOETZ: Ischemia and loss of ATP in tumors following treatment with focused high energy shock waves. Br. J. Cancer 68, 26-31 (1993) MUELLER-KLIESER, W., S. WALENTA: Geographical mapping of metabolites in biological tissue with single photon imaging and quantitative bioluminescence - Invited review. Histochem. J. 25, 407-420 (1993) WALEV, I., E. MARTIN, D. JONAS, M. MOHAMADZADEH, W. MUELLER-KLIESER, L. KUNZ, S. BHAKDI: Staphylococcal alpha-toxin kills human keratinocytes by permeabilizing the plasma membrane for monovalent ions. Infec. Immun. 61, 4972-4979 (1993) MUELLER-KLIESER, W., K. SCHLENGER, C. KNOOP, S. WALENTA, M. HOECKEL, P. VAUPEL: Oxygenation status of tumours in patients. In: Bioreductive Drugs, Sensitizers, Oxygen and Radiotherapy. W. Dobrowsky (ed.), Facultas-Universitätsverlag, Vienna, Austria, 1993, pp. 31-45 MUELLER-KLIESER, W.: Pathophysiologie maligner Tumoren. Physikalische Therapie in Theorie und Praxis 10, 687-690, 1993 KARBACH, U., C.D. GERHARZ, H. GABBERT, W. MUELLER-KLIESER: Rhabdomyosarcoma spheroids with central proliferation and differentiation. Cancer Res. 52, 474-477 (1992) MAHRO, B., A. PETERMANN-HERMANN, S. WALENTA, W. MUELLER-KLIESER, V. KASCHE: Non-extractive localization and imaging of luminescent bacteria in liquid and soil samples by luminescence microscopy. Microb. Releases 1, 79-85 (1992) BREDEL-GEISSLER, A., S. WALENTA, U. KARBACH, L. VOLLRATH, W. MUELLER-KLIESER: Quantitative correlation between proliferation, oxygen consumption, and cellular morphology of cultured EMT6 tumor cells. J. Cell. Physiol. 153, 44-52 (1992) SCHREZENMEIR, J., L. GERÖ, C. LAUE, J. KIRCHGESSNER, A. MÜLLER, A. HÜLS, R. PASSMANN, H.J. HAHN, L.A. KUNZ, W. MUELLER-KLIESER, J.J. ALTMAN: The role of oxygen supply in islet transplantation. Transpl. Proc. 24, 2925-2929 (1992) KUHNLE, G.E.H., M. DELLIAN, S. WALENTA, W. MUELLER-KLIESER, A.E. GOETZ: Simultaneous high resolution measurement of ATP and blood flow in experimental tumors. J. Natl. Cancer Inst. 84, 1642-1647 (1992) WALENTA, S., M. DELLIAN, A. GOETZ, W. 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MANZ: Intralienales Milieu, Durchblutung und Sauerstoff-Aufnahme der Milz bei Heinz-Körper-Anämie. In: Atemgaswechsel und O2-Versorgung der Organe, J. Grote und E. Witzleb (Hrsg.), Steiner Verlag, Wiesbaden, 1984 DAVE, S., P. VAUPEL, W. MUELLER-KLIESER, K. BLENDSTRUP: Temperature distribution in peripheral s. c. tumors in rats. Proceedings of the 4th International Symposium on Hyperthermic Oncology, Vol. 1, pp. 503 - 506, J. Overgaard (ed.), Taylor and Francis, London, 1984 VAUPEL, P., W. MUELLER-KLIESER, J. OTTE, R. MANZ, F. KALLINOWSKI: Blood flow, tissue oxygenation, and pH-distribution in malignant tumors upon localized hyperthermia Strahlentherapie 159, 73 - 81 (1983) MUELLER-KLIESER, W., G. THEWS, R.M. SUTHERLAND, P. VAUPEL: Recommendations for using the standardized terminology of respiratory physiology in radiation research Radiat. Res. 96, 411 - 415 (1983) VAUPEL, P., W. MUELLER-KLIESER, H. 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